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Instead, oxidative stress appears to be the underlying mechanism of glutamate-induced beta-cell death
Amram, Shoshik
The estimated treatment ratios of the mean AUC 0 of cagrilintide in each of the renal impairment groups to the normal renal function group were 1.23 (90% CI, 0.911.66) for the mild renal impairment group, 1.18 (90% CI, 0.871.59) for the moderate renal impairment group and 1.21 (90% CI, 0.871.68) for the severe renal impairment group
Drug conjugation strategies include covalent or non-covalent attachment of the therapeutic to the carrier, ensuring stability in circulation
doi: 10.2337/db08-0349
