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Mechanistically, DMF regulates the expression of factors involved in the de novo cysteine synthesis (CBS), cystine uptake (SLC7A11), and GSH generation (GCLC, GCLM) through NRF2-dependent and independent pathways
The copper(II)-catalyzed oxidation of glutathione
doi: 10.1016/j.freeradbiomed.2013.07.041
(PubMed) 53
