5-Amino-1MQ
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Description
Oncogenic mutations, such as those in KRAS, EGFR, TP53, LKB1, and KEAP1, drive these alterations through distinct mechanisms affecting glucose metabolism, mitochondrial function, redox homeostasis, and nutrient sensing
Therefore, mutations in the TNSALP gene result in a decrease in hydroxyapatite production, leading to impaired bone mineralization and decreased bone mass [41]
Maniko J
doi: 10.1093/molehr/gap059 137
Bone acquisition in adolescence
