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Knockdown of NCOA4 inhibits ferroptosis in various tumor cell lines, which could be correlated with reduced intracellular free iron pools ( SystemX c /glutathione axis SystemX c is a heterodimer cell surface amino acid transporter extensively located in the cell membrane, which is a vital component of the cellular antioxidant system (Sato et al., 1999)

[DOI] [PMC free article] [PubMed] [Google Scholar] 195.Chen Y, Zhang L, Zhang Y, Bai T, Song J, Qian W, Hou X

doi:10.31491/apt.2020.03.014

Mitochondrial biogenesis (Mitochondrial biogenesis, MB), as a way of mitochondrial self-renewal, regulates the number, size, and quality of mitochondria (Ploumi et al., 2017)