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Description
Native IGF-1 binds IGFBP-3, the dominant carrier protein in circulation, with a dissociation constant in the low nanomolar range (Kd approximately 0.1 to 1 nM in most published binding assays)
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Hecht J, Kopetz S , Welling T, Morelli MP, Molina JR, Kirtane K, Oberstein PE, Greenwald DR, Lin Y, Mardiros A, Beutner K, Lozac'hmeur A, Salahudeen A, Liechty KB, Vong J, Ng EW, Maloney DG, Go WY, Welch JS, Simeone DM

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