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Artesunate affects t antigen expression and survival of virus-positive merkel cell carcinoma

Magtanong L, Ko P-J, To M, Cao JY, Forcina GC, Tarangelo A, et al

In practice, conversion requires multiple enzymes (MTR, MTRR, SHMT, MTHFR, MTHFS) all working properly, plus adequate B12, B6, riboflavin, and glutathione

Clin Cancer Res 11:84258430

This generates GSSG, often called oxidized GSH, which is reduced by GSH reductase