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This is especially true for gastrointestinal issues such as: Acid reflux Gastric irritation Ulcer-related discomfort Animal studies on gastric ulcers have shown visible healing within 7 to 14 days, with significant reduction or complete closure of lesions

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To date, it has been demonstrated that opioids, along with NSAIDs, are among the most common and effective analgesic drugs, owing to their rapid and powerful activity