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Description
Severe intracranial (superior sagittal sinus) hypertension, portal and caval hypertension, and aortal hypotension were attenuated/eliminated
Takaya, K., Asou, T
The goal of the 3R Principle is to avoid animal experiments altogether (Replacement) and to limit the number of animals (Reduction) and their suffering (Refinement) in tests to an absolute minimum
2333, Jul
This methodological advancement paves the way for future preclinical studies evaluating therapeutic strategies for cerebrovascular protection in aging
