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Treatment was discontinued and follow-up was initiated when the Global Aesthetic Improvement Scale (GAIS) score reached 2 or the Melasma Area and Severity Index (MASI) score was reduced by 50%

designed an 18 nm negatively charged three-component nanohybrid system, AuNPs@POM@PEG, built on gold nanoparticles
These findings underscore the multifaceted role of ROS as key modulators of cell fate decisions [16, 550]

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