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Description
CO exerts an anti-inflammatory effect by inhibiting IB (IKK) kinase activity, thereby stabilizing IB and preventing NFB from translocating to the nucleus, which reduces the transcriptional priming of NLRP3 and pro-inflammatory cytokines

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doi: 10.1186/s40168-022-01458-x 33 GuoCXieSChiZZhangJLiuYZhangLet al

10.2174/138920110790909650 Curr

These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going
