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In brief, the immune cell response is mediated by four activating receptors FcRI, FcRIIA, FcRIIC (encoded by a pseudogene that is expressed only in select individuals owing to allelic polymorphism) and FcRIIIA that signal through intracellular immunoreceptor tyrosine-based activation motifs, and one inhibitory receptor (FcRIIB) that signals through an intracellular immunoreceptor tyrosine-based inhibitory motif

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Sixteen weeks later, David played his first competitive game since the injury

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