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10.3390/brainsci11091235 93 MaggioM

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In addition, it should also be noted that many of the reported AEs (e.g., restlessness, nervousness, excitement, insomnia, muscle tremors, chaotic thought and speech psychomotor agitation, cardiac arrhythmias) can be considered to be caused by the effects of excessively consumed caffeine, also including sources other than EDs

Ezcurra M et al (2018) C

That increases the autophagy (to fuel the metabolic demands), the amplification of parenchymal injury and the development of classic phenotypic features of activated HSCs/myofibroblasts