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The transfected cells were added with the final 10 nM rapamycin or 0.01% DMSO for 24 h before the EV preparation for chemical dimerization

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Cyclosporine: A review

By addressing these critical challenges and highlighting recent advances, this review serves as a roadmap for the development of next-generation peptide and protein therapeutics with improved stability and efficacy, and enhanced patient adherence, which is needed to fully realize the true potential of this class of therapeutics

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