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There are multiple ways by which Mtb can worsen HIV infection including T cell exhaustion, GSH depletion, granuloma formation, and upregulation of TNF- production

These events were reported early during therapy, and tended to be transient and/or responsive to dosage reduction

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Novel delivery of SN38 markedly inhibits tumor growth in xenografts, including a camptothecin-11-refractory model

Evaluation of the metabolic characteristics of pancreatic cancer patients compared to healthy individuals, using Principal Component Analysis (PCA), showed a notable decrease in serum levels of -hydroxybutyrate, -hydroxyisovalerate, lactate, and trimethylamine-N-oxide (TMAO)